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| Fayez Sarofim & Co. US Men's Clay Court Championship | ||
| Surface: Clay | Date: Apr. 9 - Apr. 15 | Seed: 6 |
| Round | Opponent | W / L | Result |
| First Round | Ernesto Escobedo | Win | 3-6, 7-6 (7-5), 6-2 |
| Second Round | Frances Tiafoe | Win | 6-3, 6-4 |
| Quarterfinals | John Isner | Win | 7-6 (7-4), 4-6, 7-6 (7-5) |
| Semifinals | Taylor Fritz | Win | 7-5, 6-7 (4-7), 6-2 |
| Final | Tennys Sandgren | Win | 7-6 (7-2), 2-6, 6-4 |
| Miami Open presented by Itau | ||
| Surface: Hard | Date: Mar. 20 - Apr. 1 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Victor Estrella Burgos | Win | 6-3, 6-3 |
| Second Round | Adrian Mannarino | Win | 6-3, 6-3 |
| Third Round | Pablo Carreno Busta | Loss | 4-6, 4-6 |
| BNP Paribas Open | ||
| Surface: Hard | Date: Mar. 7 - Mar. 18 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Daniil Medvedev | Loss | 6-7 (0-7), 4-6 |
| Delray Beach Open | ||
| Surface: Hard | Date: Feb. 19 - Feb. 25 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Nikoloz Basilashvili | Win | 6-3, 6-4 |
| Second Round | Milos Raonic | Win | 6-2, 6-4 |
| Quarterfinals | Evgeny Donskoy | Win | 6-1, 6-4 |
| Semifinals | Peter Gojowczyk | Loss | 6-7 (3-7), 3-6 |
| New York Open | ||
| Surface: Hard | Date: Feb. 12 - Feb. 18 | Seed: 7 |
| Round | Opponent | W / L | Result |
| First Round | Adrian Menendez-Maceiras | Loss | 6-1, 3-6, 6-7 (7-9) |
| Australian Open | ||
| Surface: Hard | Date: Jan. 15 - Jan. 28 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Denis Kudla | Loss | 7-6 (7-5), 3-6, 6-7 (3-7), 2-6 |
| ASB Classic | ||
| Surface: Hard | Date: Jan. 1 - Jan. 13 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Liam Caruana | Win | 7-5, 7-6 (7-4) |
| Second Round | Roberto Bautista Agut | Loss | 6-2, 2-6, 1-6 |
| Brisbane International presented by Suncorp | ||
| Surface: Hard | Date: Dec. 31 - Jan. 7 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Alex De Minaur | Loss | 6-7 (7-9), 4-6 |
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