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| Moselle Open | ||
| Surface: Hard | Date: Sep. 18 - Sep. 24 | Seed: 3 |
| Round | Opponent | W / L | Result |
| First Round | Bye |
| US Open | ||
| Surface: Hard | Date: Aug. 28 - Sep. 10 | Seed: 16 |
| Round | Opponent | W / L | Result |
| First Round | Ruben Bemelmans | Win | 6-3, 6-4, 6-4 |
| Second Round | Jared Donaldson | Win | 7-5, 6-4, 4-6, 3-6, 6-4 |
| Third Round | Mikhail Kukushkin | Win | 2-6, 6-3, 6-4, 6-4 |
| Fourth Round | Diego Schwartzman | Loss | 6-7 (3-7), 5-7, 6-2, 2-6 |
| Coupe Rogers | ||
| Surface: Hard | Date: Aug. 7 - Aug. 13 | Seed: 13 |
| Round | Opponent | W / L | Result |
| First Round | Jared Donaldson | Loss | 6-7 (5-7), 6-7 (8-10) |
| Citi Open | ||
| Surface: Hard | Date: Jul. 31 - Aug. 6 | Seed: 7 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Tommy Paul | Loss | 6-7 (6-8), 3-6 |
| Wimbledon | ||
| Surface: Grass | Date: Jul. 3 - Jul. 16 | Seed: 14 |
| Round | Opponent | W / L | Result |
| First Round | Malek Jaziri | Win | 6-7 (5-7), 6-4, 6-4, 7-6(7-2) |
| Second Round | Jerzy Janowicz | Loss | 6-7 (4-7), 6-7 (5-7), 6-3, 1-6 |
| Gerry Weber Open | ||
| Surface: Grass | Date: Jun. 19 - Jun. 25 | Seed: 6 |
| Round | Opponent | W / L | Result |
| First Round | Jan-Lennard Struff | Win | 1-6, 6-3, 6-4 |
| Second Round | Florian Mayer | Loss | 7-6 (8-6), 4-6, 3-6 |
| MercedesCup | ||
| Surface: Grass | Date: Jun. 12 - Jun. 18 | Seed: 4 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Jan-Lennard Struff | Win | 4-6, 7-6 (7-5), 7-6 (10-8) |
| Quarterfinals | Philipp Kohlschreiber | Win | 6-4, 2-6, 6-3 |
| Semifinals | Benoit Paire | Win | 7-6 (7-5), 7-5 |
| Final | Feliciano Lopez | Win | 4-6, 7-6 (7-5), 6-4 |
| Roland Garros | ||
| Surface: Red Clay | Date: May 28 - Jun. 11 | Seed: 16 |
| Round | Opponent | W / L | Result |
| First Round | Julien Benneteau | Win | 7-6 (8-6), 3-6, 4-6, 6-3, 6-4 |
| Second Round | Thomaz Bellucci | Win | 7-6 (7-5), 6-1, 6-2 |
| Third Round | Albert Ramos-Vinolas | Loss | 2-6, 6-3, 7-5, 2-6, 1-6 |
| Internazionali BNL d'Italia | ||
| Surface: Red Clay | Date: May 14 - May 21 | Seed: 11 |
| Round | Opponent | W / L | Result |
| First Round | Sam Querrey | Loss | 6-7 (6-8), 6-7 (8-10) |
| Mutua Madrid Open | ||
| Surface: Red Clay | Date: May 6 - May 14 | Seed: 13 |
| Round | Opponent | W / L | Result |
| First Round | Pierre-Hugues Herbert | Loss | 6-7 (5-7), 7-6 (7-4), 3-6 |
| Gazprom Hungarian Open | ||
| Surface: Red Clay | Date: Apr. 24 - Apr. 30 | Seed: 1 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Jiri Vesely | Win | 6-3, 4-6, 7-6 (7-4) |
| Quarterfinals | Martin Klizan | Win | 6-4, 6-3 |
| Semifinals | Paolo Lorenzi | Win | 6-2, 7-5 |
| Final | Aljaz Bedene | Win | 6-3, 6-1 |
| Monte-Carlo Rolex Masters | ||
| Surface: Clay | Date: Apr. 16 - Apr. 23 | Seed: 11 |
| Round | Opponent | W / L | Result |
| First Round | Ryan Harrison | Win | 6-2, 6-4 |
| Second Round | Paolo Lorenzi | Win | 6-2, 6-4 |
| Third Round | Adrian Mannarino | Win | 3-0 Retired |
| Quarterfinals | Pablo Cuevas | Win | 6-0, 3-6, 7-5 |
| Semifinals | Albert Ramos-Vinolas | Loss | 3-6, 7-5, 1-6 |
| Miami Open presented by Itau | ||
| Surface: Hard | Date: Mar. 21 - Apr. 2 | Seed: 11 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Donald Young | Loss | 2-6, 4-6 |
| BNP Paribas Open | ||
| Surface: Hard | Date: Mar. 9 - Mar. 19 | Seed: 14 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Jan-Lennard Struff | Win | 6-3, 6-2 |
| Third Round | Donald Young | Loss | 4-6, 6-1, 3-6 |
| Dubai Duty Free Tennis Championships | ||
| Surface: Hard | Date: Feb. 27 - Mar. 4 | Seed: 7 |
| Round | Opponent | W / L | Result |
| First Round | Adam Pavlasek | Win | 6-2, 6-2 |
| Second Round | Marius Copil | Win | 6-1, 6-4 |
| Quarterfinals | Evgeny Donskoy | Win | 6-4, 5-7, 7-6 (7-2) |
| Semifinals | Andy Murray | Loss | 5-7, 1-6 |
| Open 13 Marseille | ||
| Surface: Hard | Date: Feb. 20 - Feb. 26 | Seed: 4 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Aljaz Bedene | Win | 7-5, 7-5 |
| Quarterfinals | Daniil Medvedev | Win | 4-6, 6-1, 6-4 |
| Semifinals | Richard Gasquet | Win | 7-5, 6-3 |
| Final | Jo-Wilfried Tsonga | Loss | 4-6, 4-6 |
| ABN AMRO World Tennis Tournament | ||
| Surface: Hard | Date: Feb. 13 - Feb. 19 | Seed: 8 |
| Round | Opponent | W / L | Result |
| First Round | Philipp Kohlschreiber | Loss | 5-7, 2-6 |
| Australian Open | ||
| Surface: Hard | Date: Jan. 15 - Jan. 29 | Seed: 16 |
| Round | Opponent | W / L | Result |
| First Round | Alexander Bublik | Loss | 0-6, 6-3, 3-6, 4-6 |
| Brisbane International presented by Suncorp | ||
| Surface: Hard | Date: Jan. 1 - Jan. 8 | Seed: 6 |
| Round | Opponent | W / L | Result |
| First Round | Gilles Simon | Win | 7-6 (8-6), 7-6 (7-4) |
| Second Round | Kyle Edmund | Loss | 3-6, 1-3 Retired |
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